Laboratoire de Bioingénierie et Nanosciences

Alban Desoutter

Alban DESOUTTER

Adjoint-Technique

  • Diploma
    • 1995/1998 – Montpellier University (UM2) DEUG « sciences of material »
    • 2000/2003 – Montpellier University (UM1) Licence « public law and theorical law »
    • 2012/2013 – Montpellier University (UM1) Master 1 « general public law »
    • 2012/2013 – Montpellier University (UM1) University Degree « formation to clinical trial »
    • 2014/2016 – Montpellier University (UM) Master 1 & 2 « Physics for biomedical » (Phymed)
    • 2016/2018 – Montpellier University (UM) Master 1 & 2 « Theorical Physics – Nanosciences »
    • 2021/2022 – Montpellier University (UM) Master 1 « Infection Biology »
    • 2017-2023 – Montpellier University (UM) Phd in Physics « Brillouin spectroscopy for biological samples »
    • 2024-2025 – Montpellier University (UM) Master 1 “Numerical for Physics”

     

    Employment History

     

    • 2000: employee one year in the Demoscopie company in Paris; 2001-2006: administrative agent at the mixed union « Hérault Transport »;
    • 2007-2008: 1 year Clinical Research Associate (ARC) in the Nephrology Department of the University Hospital of Montpellier
    • 2008-2011: 3 years laboratory technician at the University Institute of Clinical Research (IURC) in Montpellier
    • 2010-2013: Clinical Research Associate in the LBN (EA4203)
    • Since 2013: technical assistant BAP A within the LBN (EA4203), Faculty of Odontology of the University of Montpellier (UM)

     

    Skills

    • VIPA based Brillouin microscopy setup
    • Mastery of Microtomograph and 3D reconstruction (Avizo, MicroView, Meshlab, FIJI, CloudCompare). Specialized in bone reconstruction on animal model (rat), densitometry and registration
    • Technic histology bone and soft tissues in routine (inclusion paraffin and resin)
    • Mastering confocal Raman microscopy, acquisition and data processing
    • Analysis of atomic force (Gwyddion) and interferometric microscope data (Fogal system)
    • Statistical analysis of data with Sigmaplot and R- PCA / LDA
    • Writing protocol clinical study, filing and follow-up of the study
    • Electromagnetic simulation on Matlab with FDTD method
    • PCA and multi variable statistical analysis
    • Languages: English (level 5); Spanish (level 2); German (level 1)
    • Excellent knowledge of law and institutions
    • Quality process and safety

     

    Other function in laboratory

     

    • 2015: rescue worker
    • 2017-2020: responsible of quality process
    • 2022: safety assistant

     

    Publications

     

    • Renaud, M., Farkasdi, S., Pons, C., Panayotov, I., Collart-Dutilleul, P. Y., Taillades, H., A. Desoutter … & Yachouh, J. (2016). A new rat model for translational research in bone regeneration. Tissue Engineering Part C: Methods, 22(2), 125-131.
    • Renaud, M., Farkasdi, S., Desoutter, A., Varga, G., Cuisinier, F., & Bousquet, P. (2016). A Rat Tail Model for Osseointegration Studies and New Bone Formation Follow-up. Journal of Cell Science & Therapy, 7(3).
    • Slimani, A., Nouioua, F., Desoutter, A., Levallois, B., Cuisinier, F. J., Tassery, H., … & Salehi, H. (2017). Confocal Raman mapping of collagen cross-link and crystallinity of human dentin–enamel junction. Journal of Biomedical Optics, 22(8), 086003..
    • Desoutter, A., Yusuf Solieman, O., Subsol, G., Tassery, H., Cuisinier, F., & Fages, M. (2017). Method to evaluate the noise of 3D intra-oral scanner. Plos one, 12(8), e0182206.
    • Al-Obaidi, R., Salehi, H., Desoutter, A., Bonnet, L., Etienne, P., Terrer, E., … & Cuisinier, F. J. G. (2018). Chemical & nano-mechanical study of artificial human enamel subsurface lesions. Scientific reports, 8(1), 1-8.
    • Dutilleul, P. Y. C., Desoutter, A., Cueto-Diaz, E., Fatima, N., Gerecsei, T., Gergely, C., … & Cuisinier, F. (2018, March). Association of po4 loaded porous silicon microparticles with nacre proteins enhances mineralized bone formation in vivo. In Porous Semiconductors-Science and Technology 2018.
    • Barthélemi, S., Desoutter, A., Souaré, F., & Cuisinier, F. (2019). Effectiveness of anchorage with temporary anchorage devices during anterior maxillary tooth retraction: A randomized clinical trial. The korean journal of orthodontics, 49(5), 279-285.
    • Desoutter, A., Slimani, A., Al‐Obaidi, R., Barthélemi, S., Cuisinier, F., Tassery, H., & Salehi, H. (2019). Cross striation in human permanent and deciduous enamel measured with confocal Raman microscopy. Journal of Raman Spectroscopy, 50(4), 548-556.
    • Al-Obaidi, R., Salehi, H., Desoutter, A., Tassery, H., & Cuisinier, F. (2019). Formation and assessment of enamel subsurface lesions in vitro. Journal of Oral Science, 18-0174.
    • Al-Obaidi, R., Tassery, H., Cloitre, T., Gergely, C., Cuisinier, F., & Salehi, H. (2019, February). Confocal Raman microscopy and non linear microscopy to study human enamel incipient lesions. In Lasers in Dentistry XXV (Vol. 10857, pp. 29-33). SPIE.
    • Durand, J. C., Slangen, P., Montrésor, S., Desoutter, A., Solieman, O. Y., Fages, M., & Picart, P. (2021). Behavior of CAD/CAM ceramic veneers under stress: A 3D holographic study. Journal of the mechanical behavior of biomedical materials, 118, 104436.
    • Desoutter, A., Slimani, A., Tassery, H., Cuisinier, F., Sauro, S., Salehi, H., & Panayotov, I. (2021). Confocal Raman data analysis of tufts and spindles at the human dentin-enamel junction. Archives of Oral Biology, 131, 105262.
    • Desoutter, A., Subsol, G., Fargier, E., Sorgius, A., Tassery, H., Fages, M., & Cuisinier, F. (2022). New method to analyze resolution acquisition for intraoral scanners.
    • Belaid, H., Barou, C., Collart-Dutilleul, P. Y., Desoutter, A., Kajdan, M., Bernex, F., … & Bechelany, M. (2022). Fabrication of Radio-Opaque and Macroporous Injectable Calcium Phosphate Cement. ACS Applied Bio Materials.
    • Desoutter, A., Panayotov, I., Cuisinier, F., & Carayon, D. (2022). Human tooth enamel tuft drapes revealed by microtomography. Archives of Oral Biology, 141, 105487.
    • Desoutter, A., Cases, O., Collart Dutilleul, P. Y., Simancas Escorcia, V., Cannaya, V., Cuisinier, F., & Kozyraki, R. (2022). Enamel and dentin in Enamel renal syndrome: A confocal Raman microscopy view. Frontiers in physiology, 1748.
    • Desoutter, A., Felbacq, D., Gergely, C., Varga, B., Bonnet, L., Etienne, P., … & Rufflé, B. (2023). Properties of dentin, enamel and their junction, studied with Brillouin scattering and compared to Raman microscopy. Archives of Oral Biology, 105733.
    • Fatima, N., Salehi, H., Cueto-Díaz, E. J., Desoutter, A., Cuisinier, F., Cunin, F., & Collart-Dutilleul, P. Y. (2023). Nanostructured Porous Silicon for Bone Tissue Engineering: Kinetics of Particle Degradation and Si-Controlled Release. Journal of Functional Biomaterials, 14(10), 493.
    • Shah, S. A., Salehi, H., Cavaillès, V., Fernandez, F., Cuisinier, F., Collart-Dutilleul, P. Y., & Desoutter, A. (2023) Characterization of Rat Vertebrae Cortical Bone Microstructures Using Confocal Raman Microscopy Combined to Tomography and Electron Microscopy. Annals of Anatomy.
    • Desoutter, A., Subsol, G., K. Bouchiha, I. Benmoumen, Fages, M., & Cuisinier, F. (2024) « Unified protocol to evaluate intraoral scanner resolution, trueness and precision: the RTP-protocol”. Metrology and Measurement.
    • Desoutter, A., Vialla, R., Cuisinier, F., Messat, Y., Salehi, H., Rousseau, E., & Rufflé, B. (2024, March). Interest of diffractive mask in a VIPA based Brillouin spectrometer for biological sample. In Optical Elastography and Tissue Biomechanics XI (Vol. 12844, p. 128440E). SPIE.
    • Chouaib, B., Desoutter, A., Cuisinier, F., & Collart-Dutilleul, P. Y. (2024). Dental Pulp Stem Cell Conditioned Medium Enhance Osteoblastic Differentiation and Bone Regeneration. Stem Cell Reviews and Reports, 1-14.
    • Collart-Dutilleul, P. Y., Piglionico, S., Younes, R., Messat, Y., Garrabé, S., Salehi, H., … & Desoutter, A. (2025). Raman confocal microscopy atlas of Human tooth. Archives of Oral Biology, 106189.
    • Al-Obaidi, R., Desoutter, A., Salehi, H., Cuisinier, F., Jacquot, B., & Tassery, H. (2025). Non-Invasive Treatment of Reversible Caries Lesions in Vitro: A Novel Era in Denal Practice. Al-Rafidain Journal of Medical Sciences (ISSN 2789-3219), 8(1), 201-207.
    • Desoutter, A., Younes, R., Vialla, R., Cuisinier, F., Messat, Y., Autran, D., … & Rufflé, B. (2025, March). A versatile Brillouin microscope for fast mechanical mapping: from cells to calcified tissues. In Optical Elastography and Tissue Biomechanics XII (Vol. 13321, pp. 58-62). SPIE.
    • A. Desoutter, R. Vialla, F. Cuisinier, Y. Messat, H. Salehi, E. Rousseau, Benoit Ruffle. VIPA based high-contrast high-efficiency two-stage Brillouin imaging spectrometer using a single diffraction mask. Journal Applied Physics
    • Younes, R., Collart‐Dutilleul, P. Y., Fernandez, F., Cuisinier, F., & Desoutter, A. (2025). Chemical and Structural Organization of Pig Tooth Enamel and Dentin by Confocal Raman Microscopy: A Comparison With Human. Journal of Raman Spectroscopy.
    • Biomechanical mapping of porcine dentin and branches with Brillouin confocal VIPA-based microscopy. Richard Younes, Frédéric Cuisinier, Benoit Rufflé, Rémy Vialla, Shahid Ali Shah, Pierre-Yves Collart-Dutilleul, Alban Desoutter. Annals of anatomy (2025)

     

    Submit but not publish:                  

    • Distribution and size of scallop at the human dentin enamel junction reveal with micro tomography. Pierre-Yves Collart-Dutilleul, T. Cloitre, D. Carayon, A. Slimani, H. Salehi, H. Tassery, F. Cuisinier, and  A. Desoutter. Submitted in journal of physiology (in review)
    • Non invasive methods for characterization old teeth enamel and dentine condition, applied to Rhinocéros 4 chalcolithic cave (Péret, France) samples. Alban Desoutter, Michel Ramonda, Pierre-Yves Collart-Dutilleul, Hamideh Salehi, Frédéric Cuisinier and Delphine Carayon. Dental Anthropology Journal (in review)

    Metrics

    h-index: 9; i10-index: 8

     

    International Conference participation

     

    • IDS 2012 (Cologne, Germany)
    • SPIE 2014 (San Francisco, USA)
    • ICFOD congress 2012 et 2014 (Montpellier, France)
    • AADR 2016 (Los Angeles, USA)
    • International Conference on BioMedical Photonics 2018 (Grande Motte, France)
    • SPIE 2019 (San Francisco, USA)
    • Cost BioBrillouin (2017 Perugia, Italy, 2018 Porto, Portugal)
    • SPIE 2022 (San Francisco, USA)
    • Enamel Symposium 2022 (Pittsburg, USA)
    • IADR 2022 (Marseille, France)
    • Cnesbo 2022 (Toulouse, France)
    • 1st Conference on Brillouin light Scattering for life science and biomedical applications 2022 (Lyon, France)
    • WCLI 2023 Formum (Athens, Greece)
    • JFTBM 2023 (Sète, France)
    • Spie 2024 (San Francisco, USA)
    • N4M 2024 (Genova, Italy)
    • SPIE 2025 (San Francisco, USA)

     

    Communication

     

    • Structure and chemical composition of the dentin-enamel junction analyzed by Confocal Raman Microscopy ; A. Desoutter · H. Salehi · A. Slimani · P. Marquet · B. Jacquot · H. Tassery · F. J. G. Cuisinier ; presentation SPIE 2014 (San Francisco) Lasers in Hard Tissue cession
    • Method to approximate intra oral scanner noise and resolution Desoutter, A., Solieman, O. Y., Subsol, G., Fages, M., & Cuisinier, F. (2019, February). In Lasers in Dentistry XXV (Vol. 10857, p. 1085707). International Society for Optics and Photonics.
    • Dental Defects In Enamel Renal Syndrome: A Confocal Raman Microscopy Approach. Alban Desoutter, Olivier Cases, Pierre-Yves Collart-Dutilleul, Frédéric Cuisinier, Renata Kozyraki. In Enamel Symposium X (Pittsburgh).
    • Microscopie Brillouin pour la biologie (2024, April). Fédération de Physique pour la Biologie (Grenoble) ; (2024, Octobre), NUMEV ( univrsité Montpellier). Alban Desoutter, Benoit Rufflé.
    • UTT (Université du Tiers Temps) 2023: dental histology ; 2024: Raman and Brillouin for life ;

     

    Poster

     

    • Porous silicon and dental pulp stem cells: a new tissue engineering method, Renaud, Matthieu ;Collart Dutilleul, Pierre-yves ;Pons, Coline ; Panayotov, Ivan ;  Desoutter, Alban ;  Middendorp, Elodie ;  Bousquet, Philippe ;  Cuisinier, Frederic  ; JADR 2014 Poster Session
    • Dental Defects In Enamel Renal Syndrome: A Confocal Raman Microscopy Approach. Alban Desoutter, Olivier Cases, Pierre-Yves Collart-Dutilleul, Frédéric Cuisinier, Renata Kozyraki. In Enamel Symposium X (Pittsburgh).
    • Intra-oral scanner investigation for shovel-shaped incisor analysis in anthropology. Alban Desoutter, Aurélien Ferré, Paul Monsarrat, Rémi Esclassan, Delphine Carayon. IADR, 2022,

     

    Reviewing

     

    • Luís, G., Silva, H., Silveira, J., Manteigas, V., Mata, A., Marques, D., … & Pessanha, S. (2019). Evaluation of enamel demineralization and fluorine uptake caused by gustatory stimulants of salivary secretion (GSSS) using Raman spectroscopy and proton induced gamma‐ray emission (PIGE). Journal of Raman Spectroscopy, 50(3), 380-386.
    • Younis, S. H., Obeid, R. F., & Ammar, M. M. (2020). Subsurface enamel remineralization by Lyophilized Moringa leaf extract loaded varnish. Heliyon, 6(9), e05054.
    • Buzalaf, M. A. R., Levy, F. M., Gomes, B., Valle, A. D., Trevizol, J. S., Magalhães, A. C., & Joiner, A. (2021). Protective effect of calcium silicate toothpaste on enamel erosion and abrasion in vitro. Heliyon, 7(4), e06741.
    • Saghiri, M. A., Sheibani, N., Kawai, T., Nath, D., Dadvand, S., Amini, S. B., … & Morgano, S. M. (2022). Diabetes negatively affects tooth enamel and dentine microhardness: An in-vivo study. Archives of Oral Biology, 139, 105434.
    • Ryniewicz, W., Bojko, Ł., & Ryniewicz, A. M. (2022). Evaluation of geometric parameters of the stomatognathic system using radiological imaging. Metrology and Measurement Systems, 29(3).
    • Dixit, S., Shyagali, T. R., & Kambalyal, P. (2023). Evaluation of the correlation between facial index and the cortical bone thickness of the maxilla and mandible—A computer tomography based study. Archives of Oral Biology, 146, 105606.
    • Sipovac, M., Petrovic, B., Amzirkov, M., & Stefanovic, S. (2023). Enamel incremental markings in the deciduous teeth of children from the Early Bronze and modern ages. Archives of Oral Biology, 148, 105635.
    • Thermal behavior of modern and archaeological enamel and dentin by in situ temperature dependent Raman spectroscopy
    • Henriksen, J. S., Lauridsen, E., Gjørup, H., Al-Imam, H., Lundgren, T., Sabel, N., … & Hermann, N. V. (2023). A pilot study comparing optical coherence tomography, radiography, clinical photography, and polarisation microscopy for studies of hypomineralisation disturbances in enamel. Heliyon, 9(2).
    • Fakheran, O., Fischer, K. R., & Schmidlin, P. R. (2023). Enamel Matrix Derivatives as an Adjunct to Alveolar Ridge Preservation—A Systematic Review. Dentistry Journal, 11(4), 100.
    • Gehrke, S. A., Scarano, A., Cortellari, G. C., Fernandes, G. V. O., Mesquita, A. M. M., & Bianchini, M. A. (2023). Marginal Bone Level and Biomechanical Behavior of Titanium-Indexed Abutment Base of Conical Connection Used for Single Ceramic Crowns on Morse-Taper Implant: A Clinical Retrospective Study. Journal of Functional Biomaterials, 14(3), 128.
    • Chen, Y., & Hu, Y. (2023). Wnt Signaling Activation in Gingival Epithelial Cells and Macrophages of Experimental Periodontitis. Dentistry Journal, 11(5), 129.
    • Mahmoud, A., Elbasuney, S., & El-Sharkawy, Y. H. (2023). Instant identification of dental white spot using K-means algorithm via laser-induced fluorescence and associated hyperspectral imaging. Journal of Photochemistry and Photobiology B: Biology, 112749.
    • Gehrke, S. A., Scarano, A., Cortellari, G. C., Fernandes, G. V. O., Watinaga, S. E., & Bianchini, M. A. (2023). Evaluation of Behavior of Castable versus Machined Solid Abutments for Morse Tapper Implant Connection: A Clinical Retrospective Study. Medicina, 59(7), 1250
    • Chen, S., Hong, X., Ye, Z., Wu, M., Chen, L., Wu, L., … & Zhao, S. (2023). The effect of root canal treatment and post-crown restorations on stress distribution in teeth with periapical periodontitis: a finite element analysis. BMC Oral Health, 23(1), 973.
    • Demircan, B., & Demir, P. (2023). 3D Finite Element Analysis of Stress Distribution in Dental Tissues and Materials as a Result of Oblique and Horizontal Forces after Regenerative Endodontic Treatment. Available at SSRN 4492944.
    • Wang, C., Lai, G., Xiang, H., Wang, J., Han, Y., & Zhang, D. (2023). Study on near-infrared diffused reflectance imaging for early caries detection.
    • Towle, I., & Loch, C. (2024). Variation in enamel prism size in primate molars. Archives of Oral Biology, 105895.
    • AlShukri, Y., Visser, I. N., Wiig, Ø., & Loch, C. (2025). Macromorphology, Microstructure, Mechanical Properties, and Elemental Composition of Enamel and Dentine in the Eurasian Otter Lutra lutra. International Journal of Zoology, 2025(1), 2548475.Barnard, P., McFarlane, G., Deter, C., Loch, C., & Mahoney, P. (2025).
    • The periodicity of enamel laminations in human deciduous molars. Archives of Oral Biology, 171, 106164.Katebifar, S., Clark, K., Rosenberg, B., Truhlar, M., & Deymier, A. Probable Relation between Structure & Composition of the Dentin-Enamel Junction (Dej) and Dentinogenesis Imperfecta (Dgi). Available at SSRN 4993215.
    • Leclercq, M., Vallet, M., Reiss, T., Berdal, A., & Vennat, E. (2025). Revealing Dentin Multiscale Structures Using High-Resolution Transmission Electron Microscopy. Journal of Dental Research, 00220345251361912.

    Supervision internship

    2016-2017 Master 1 Phymed (univ Montpellier):

    • Aarrass Hanna « dental enamel studied by Raman microscopy »

    2017-2018 Master 1 phymed (univ Montpellier):

    • Yosra Hmadi « Interpretation of 3D holography data on veneered and natural teeth »
    • Laura Ratsimbason « Study and development of the optical scheme of a Brillouin scattering microscope »
    • Ayoub Khattabi « Determination of the resolution of intra-oral cameras »
    • Modou Abdoulaye Ndao « Development of a reliable technique for assessing the roughness of dental enamel »

    2017/2018 licence CMI

    • Liam Van Norden: « Méthode FDTD pour la simulation de la propagation des ondes électromagnétiques »

    2018-2019 Master 1 phymed (univ Montpellier):

    • Farouq ABadak: « Study of emax press denture ceramics with confocal Raman microscopy. »

    2019/2020 Master 1 phymed (univ Montpellier):

    • Adam Garouche: « Study of white spots in dental enamel by confocal Raman microscopy and comparison with other techniques »

    2020/2021 Master 1 phymed (univ Montpellier):

    • Sanaa Takun: « Confocal Raman Microscopy and Micro-CT Mapping of Tooth Sections with Email-Rein Syndrome »
    • Ikram Benmoumen: « Study of the properties of some intraoral cameras, used in CAD/CAM to reconstruct dental prostheses »

    2021/2022 Master 1 phymed (univ Montpellier):

    • Ikram Ziani: « Realization of a scan of a fixed cell by confocal Brillouin microscopy »
    • Adnane Zerguit: « Development of a patching device for IOS camera on full arcade »
    • Hafsa Djongo Abba: « Study of chalcolithic premolars by X-ray microtomography and Confocal Raman microscopy »

    2023/2024 Master 1 Phymed (univ Montpellier):

    • Noura Soilihi « study of mecanical properties study of dictyostelium discoideum »

    2024/2025 Master 1 Ines Naima

    • Brillouin micrscopy on spinal cord

     

    Education

     

    • April 2024 and 2025. Short formation (2 days) “initiation to Brillouin microscopy” at Montpellier University
    • April 2025. Short formation (2 days) “Raman microscopy for Biology” at Montpellier University

    Training

    • Animal experimentation – level 2
    • Laser security – level 3
    • first aid PSC1

    Social networks

    https://www.linkedin.com/in/alban-desoutter-a3b478161/

    https://www.researchgate.net/profile/Alban-Desoutter

    https://scholar.google.com/citations?user=wsx7J3IAAAAJ&hl=fr

    Newspaper/media publications for the general public

    Drapes:

    About Brillouin: 

    Other: 

Mel: alban.desoutter@umontpellier.fr

Tel: 06 74 63 52 15